Description

2-(tert-Butoxycarbonyl)-5-Chlorobenzoic Acid is a high-purity, protected benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in the orthogonal protection of the carboxylic acid group, enabling selective reactions and the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides.
• Peptide Chemistry: Used in the synthesis of peptide analogs and conjugates where selective deprotection is required.
• Material Science Research: Monomer or intermediate for creating specialized polymers and organic electronic materials.
• Chemical Biology: Tool compound for probe and linker synthesis in bioconjugation and labeling applications.
• Academic & R&D: Versatile reagent for methodological development and exploring new synthetic routes in organic chemistry.

Basic Information

Product Name	2-(tert-Butoxycarbonyl)-5-Chlorobenzoic Acid
CAS No.	2172572-27-7
Molecular Formula	C12H13ClO4
Molecular Weight	256.68 g/mol
Synonyms	5-Chloro-2-[(2-methylpropan-2-yl)oxycarbonyl]benzoic acid; Boc-5-Chlorosalicylic Acid (common); 5-Chloro-2-(tert-butoxycarbonyl)benzoic Acid; 2-Boc-5-Chlorobenzoic Acid; tert-Butyl 5-chloro-2-carboxybenzoate; 2-(Boc)-5-Cl-BA; 2-(tert-Butoxycarbonyl)-5-chlorobenzoate
EINECS	Contact for details

Quality Control

Our 2-(tert-Butoxycarbonyl)-5-Chlorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.