Description

1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-[(1E)-2-(2-Methyl[1,1'-Biphenyl]-3-Yl)Ethenyl]- is a specialized organoboron reagent featuring a biphenyl-substituted ethenyl group, which is crucial for advanced cross-coupling reactions. This compound matters for its role as a key synthetic intermediate in constructing complex molecular architectures, particularly in pharmaceutical and materials science research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for Suzuki-Miyaura coupling and other palladium-catalyzed transformations.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing biphenyl or extended conjugated systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for creating advanced organic semiconductors and emissive layer materials due to its conjugated structure.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and other functional materials where precise control over molecular structure is essential.
• Cross-Coupling Reactions: Primarily utilized in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds between aryl and vinyl groups.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for imaging and diagnostic applications.

Basic Information

Product Name	1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-[(1E)-2-(2-Methyl[1,1'-Biphenyl]-3-Yl)Ethenyl]-
CAS No.	2171558-33-9
Molecular Formula	C21H23BO2
Molecular Weight	318.22 g/mol
Synonyms	2-[(1E)-2-(2-Methyl[1,1'-biphenyl]-3-yl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-2-(2-Methyl-[1,1'-biphenyl]-3-yl)vinylboronic acid pinacol ester; 2-Methyl-3-vinylbiphenyl pinacol boronate; Biphenyl vinylboronic ester; Trans-2-(2'-Methylbiphenyl-3-yl)vinylboronic acid pinacol ester; CAS 2171558-33-9
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and stability, with a focus on meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity (typically by HPLC/NMR), assay, and impurity profiles are available upon request. We adhere to a quality management system to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to ensure long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0% (Area %)
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.