Description

4,6-Dichloro-2-Fluoro-3-Methoxyphenylacetonitrile is a high-value, multi-functional aromatic nitrile building block designed for advanced chemical synthesis. Its molecular structure, featuring strategically placed halogen and methoxy substituents, makes it an essential intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Ligand and Catalyst Development: Used in organic and organometallic chemistry to create specialized ligands for catalysis and materials science applications.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	4,6-Dichloro-2-Fluoro-3-Methoxyphenylacetonitrile
CAS No.	2149598-64-9
Molecular Formula	C9H6Cl2FNO
Molecular Weight	234.05 g/mol
Synonyms	2-(4,6-Dichloro-2-fluoro-3-methoxyphenyl)acetonitrile; (4,6-Dichloro-2-fluoro-3-methoxyphenyl)acetonitrile; 4,6-Dichloro-2-fluoro-3-methoxybenzyl cyanide; CAS 2149598-64-9; 4,6-Dichloro-2-fluoro-3-methoxybenzenecarbonitrile; 2-Fluoro-3-methoxy-4,6-dichlorophenylacetonitrile
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-Fluoro-3-Methoxyphenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.