Description

Potassium (3-Hydroxy-4-Methylphenyl)Trifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. This compound matters as a stable, air- and moisture-tolerant reagent that enables efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex biaryl structures. It is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for the synthesis of active pharmaceutical ingredients (APIs), liquid crystal materials, and functional polymers.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor in the scalable production of novel drug candidates, especially those containing biphenyl or substituted phenyl motifs.
• Agrochemical Development: Used in creating advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) for electronic and photonic applications.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, easy-to-handle aryl source for palladium-catalyzed C-C bond formation under mild conditions.
• Chemical Biology & Probe Development: Utilized for the site-specific incorporation of aryl groups into complex molecules for biological activity studies.
• Fine Chemical and Specialty Chemical Manufacturing: Acts as a versatile intermediate for producing dyes, pigments, and performance chemicals.

Basic Information

Product Name	Potassium (3-Hydroxy-4-Methylphenyl)Trifluoroborate
CAS No.	2149596-13-2
Molecular Formula	C7H7BF3KO
Molecular Weight	214.04 g/mol
Synonyms	Potassium (3-Hydroxy-p-tolyl)trifluoroborate; Potassium 3-Hydroxy-4-methylphenyltrifluoroborate; (3-Hydroxy-4-methylphenyl)trifluoroborate Potassium Salt; 4-Methyl-3-hydroxybenzenetrifluoroborate Potassium Salt; 3-Hydroxy-4-methylphenyl-BF3K; Potassium 4-Methyl-3-hydroxyphenyltrifluoroboronate; Borate(1-), trifluoro(3-hydroxy-4-methylphenyl)-, potassium (1:1); CAS 2149596-13-2
EINECS	Contact for details

Quality Control

Our Potassium (3-Hydroxy-4-Methylphenyl)Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC, and KF titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹H NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.