Description

5-Fluoro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl Acetate is a high-value boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to introduce fluorinated aromatic structures into advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic rings for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine atom and boronate group enable precise structural modifications.
• Material Science Research: Serves as a monomer or building block for creating advanced organic electronic materials, such as OLEDs and semiconductors, via polymerization or functionalization.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and labeled compounds for diagnostic assays and biomedical research due to its reactive boronate handle.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	5-Fluoro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl Acetate
CAS No.	2142562-01-2
Molecular Formula	C15H20BFO4
Molecular Weight	294.13 g/mol
Synonyms	2-(Acetoxymethyl)-4-fluorophenylboronic acid pinacol ester; (2-(Acetoxymethyl)-4-fluorophenyl)boronic acid pinacol ester; 4-Fluoro-2-(hydroxymethyl)phenylboronic acid pinacol ester acetate; 5-Fluoro-2-(pinacolboronato)benzyl acetate; [2-(Acetyloxymethyl)-4-fluorophenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl Acetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.