Description

Dibenzofuran, 7-Chloro-1-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-purity, functionalized dibenzofuran derivative bearing a chloro substituent and a key pinacol boronate ester group. This compound is a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in modern synthetic chemistry, enabling the formation of new carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and materials science who require precise, reliable, and scalable boronic ester reagents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient construction of biaryl and heterobiaryl structures, which are core scaffolds in many active pharmaceutical ingredients (APIs) and functional materials.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transporting or host materials in the production of advanced display and lighting technologies.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts.
• Polymer and Material Science: Incorporated into specialty polymers and advanced organic materials to modify electronic properties, thermal stability, and mechanical strength.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists in lead optimization, structure-activity relationship (SAR) studies, and route scouting.

Basic Information

Item	Details
Product Name	Dibenzofuran, 7-Chloro-1-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	2140871-50-5
Molecular Formula	C18H18BClO3
Molecular Weight	328.60 g/mol
Synonyms	7-Chloro-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)dibenzofuran; 7-Chlorodibenzofuran-1-ylboronic acid pinacol ester; 1-(7-Chlorodibenzofuran-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 7-Chloro-1-dibenzofuranboronic acid pinacol ester; (7-Chlorodibenzofuran-1-yl)boronic acid pinacol ester; PINACOL 7-CHLORODIBENZOFURAN-1-YLBORONATE; 7-Chloro-1-(pinacolatoboryl)dibenzofuran
EINECS	Contact for details

Quality Control

Our production of Dibenzofuran, 7-Chloro-1-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR (1H, 13C, 11B), and GC-MS to confirm identity, purity, and the absence of critical impurities. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.