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2-(8-Chlorodibenzo[B,D]Furan-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 2140871-41-4


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CAS No.:2140871-41-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(8-Chlorodibenzo[B,D]Furan-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound matters as a critical intermediate in cross-coupling reactions, enabling the precise construction of complex organic frameworks. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing novel active ingredients and functional molecules, where its specific substitution pattern is key to introducing the chlorinated dibenzofuran moiety.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex biaryl and heterobiaryl structures.
  • Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing dibenzofuran scaffolds.
  • Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced properties.
  • Organic Light-Emitting Diodes (OLEDs): A precursor for electron-transport materials and emissive layer components in display and lighting technologies.
  • Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
  • Material Science Research: Used to create novel polymers and small molecules with specific electronic or optical properties for advanced applications.

Basic Information

Item Details
Product Name 2-(8-Chlorodibenzo[B,D]Furan-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No. 2140871-41-4
Molecular Formula C20H19BClO3
Molecular Weight 353.63 g/mol
Synonyms 8-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)dibenzofuran; 2-(8-Chlorodibenzofuran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 8-Chlorodibenzofuran-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-8-chlorodibenzofuran; Pinacol 8-chlorodibenzofuran-4-ylboronate
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Quality Control

Every batch of 2-(8-Chlorodibenzo[B,D]Furan-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for research and process chemistry. Our quality commitment includes comprehensive analysis via HPLC, NMR (¹H and ¹³C), and mass spectrometry. Certificates of Analysis (COA) with full traceability are provided with each shipment, confirming compliance with in-house specifications developed for high-performance building blocks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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