Description

Ethanone, 1-[3-Chloro-4-Fluoro-5-(Trifluoromethyl)Phenyl]-2,2,2-Trifluoro- is a high-value, multi-fluorinated aromatic ketone building block designed for advanced chemical synthesis. This compound matters because its unique halogenated structure provides critical reactivity and stability for creating complex molecules in demanding applications. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a critical building block for developing next-generation herbicides, fungicides, and insecticides, where the fluorine and chlorine substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials, where its aromatic and fluorinated structure contributes to desired electronic properties and thermal stability.
• Polymer & Resin Modifier: Acts as a specialty monomer or cross-linking agent to introduce fluorine into polymers, improving their chemical resistance, weatherability, and surface properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecular architectures via reactions such as nucleophilic aromatic substitution and carbonyl chemistry.
• Fluorinated Dye & Pigment Intermediate: Utilized in the synthesis of specialty dyes and pigments where fluorination is required for color fastness and enhanced performance.

Basic Information

Item	Detail
Product Name	Ethanone, 1-[3-Chloro-4-Fluoro-5-(Trifluoromethyl)Phenyl]-2,2,2-Trifluoro-
CAS No.	2138407-75-5
Molecular Formula	C9H2ClF7O
Molecular Weight	294.56 g/mol
Synonyms	1-(3-Chloro-4-fluoro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone; 3-Chloro-4-fluoro-5-(trifluoromethyl)phenacyl trifluoride; 2,2,2-Trifluoro-1-[3-chloro-4-fluoro-5-(trifluoromethyl)phenyl]ethanone; 3'-Chloro-4'-fluoro-5'-(trifluoromethyl)trifluoroacetophenone; TFAP-CF3-Cl-F derivative; CAS 2138407-75-5
EINECS	Contact for details

Quality Control

Our Ethanone, 1-[3-Chloro-4-Fluoro-5-(Trifluoromethyl)Phenyl]-2,2,2-Trifluoro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.