Description

7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazole is a high-purity, advanced pharmaceutical intermediate and building block for organic synthesis. This compound is valued for its role in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those containing the benzoxazole scaffold, which is associated with diverse biological activities.
• Agrochemical Synthesis: Used in research and development for creating new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, such as OLEDs (Organic Light-Emitting Diodes) and conductive polymers.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and labeled compounds for diagnostic and biochemical research applications.
• Cross-Coupling Reactions: Specifically designed as a boronic ester partner in palladium-catalyzed Suzuki-Miyaura couplings to form biaryl and heterobiaryl structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.

Basic Information

Product Name	7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazole
CAS No.	2137501-14-3
Molecular Formula	C15H20BNO3
Molecular Weight	273.14 g/mol
Synonyms	7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazole; Benzo[d]oxazole, 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 7-(Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoxazole; 7-Benzooxazoleboronic acid pinacol ester; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoxazole
EINECS	Contact for details

Quality Control

Our 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged exposure to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.