Description

4,5-Difluoro-3-(Phenylthio)Isobenzofuran-1(3H)-One is a high-value, fluorinated heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring precise molecular modifications to develop novel materials and active pharmaceutical ingredients (APIs). It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, material science, and the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific biological pathways where fluorinated motifs enhance metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the difluoro and phenylthio groups can contribute to unique biological activity and environmental persistence profiles.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor or electron-transport material in the fabrication of advanced OLED displays and lighting, leveraging its fused aromatic structure.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis, particularly in cross-coupling and other transition metal-catalyzed reactions.
• Polymer Modification: Acts as a functional monomer or additive to introduce fluorinated and sulfur-containing units into polymers, altering their physical, chemical, and surface properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, enabling the exploration of new chemical spaces and reaction pathways.

Basic Information

Item	Details
Product Name	4,5-Difluoro-3-(Phenylthio)Isobenzofuran-1(3H)-One
CAS No.	2136287-64-2
Molecular Formula	C14H7F2O2S
Molecular Weight	277.27 g/mol
Synonyms	3-(Phenylthio)-4,5-difluoroisobenzofuran-1(3H)-one; 4,5-Difluoro-3-(phenylsulfanyl)-1,3-dihydro-2-benzofuran-1-one; 4,5-Difluoro-3-(phenylthio)phthalide; 4,5-Difluoro-3-(phenylthio)-1(3H)-isobenzofuranone; Difluorophenylthioisobenzofuranone
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-3-(Phenylthio)Isobenzofuran-1(3H)-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research and manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.