Description

1-Pyrenecarboxylic Acid-Peg2-Azide is a high-purity, functionalized chemical building block designed for advanced bioconjugation and materials science applications. This compound is engineered to provide a reliable and efficient click chemistry handle, enabling precise attachment of pyrene fluorophores to biomolecules, polymers, and surfaces. It is essential for researchers and manufacturers in the fields of biopharmaceuticals, diagnostic assay development, and advanced material synthesis who require robust, site-specific labeling and cross-linking capabilities.

Application

• Bioconjugation and Protein Labeling: Site-specific attachment of pyrene fluorophores to antibodies, peptides, and other proteins for fluorescence-based assays and imaging.
• Polymer and Dendrimer Functionalization: Modification of polymer backbones or dendrimer surfaces to introduce pyrene moieties for sensing, self-assembly, or energy transfer studies.
• Surface Immobilization and Biointerface Engineering: Crafting functionalized surfaces on chips, beads, or nanoparticles for biosensor development and microarray technology.
• Click Chemistry Synthesis: Serving as a key reagent in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create complex molecular architectures.
• Fluorescent Probe and Sensor Development: Creating sensitive molecular probes for detecting analytes, monitoring enzymatic activity, or studying molecular interactions.
• Pharmaceutical Research: Development of drug conjugates or targeted delivery systems where a trackable fluorescent label is required.

Basic Information

Product Name	1-Pyrenecarboxylic Acid-Peg2-Azide
CAS No.	2135330-58-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Pyrene-PEG2-Azide; 1-Pyrenebutanoic acid, 4-azido-α-carboxy-ω-(1-pyrenylbutanoyl)poly(oxy-1,2-ethanediyl); Azido-PEG2-pyrene; PEG2-Azide-Pyrene; 1-Pyrenebutyric acid-PEG2-azide; N3-PEG2-Pyrene; Pyrene Azide Polyethylene Glycol Derivative
EINECS	Contact for details

Quality Control

Our 1-Pyrenecarboxylic Acid-Peg2-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.