Description

Benzaldehyde, 4-(Phenylmethoxy)-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, multifunctional chemical intermediate featuring a benzaldehyde core protected with a phenylmethoxy group and a pinacol boronate ester. This compound matters because it serves as a critical building block in modern synthetic chemistry, enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. Pharmaceutical, agrochemical, and advanced material researchers need it for the efficient synthesis of complex, functionalized aromatic and heteroaromatic target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring complex biaryl or substituted aromatic structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that rely on boronic ester chemistry for structural diversification.
• Material Science Research: Building block for creating organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the development of molecular probes and bioconjugation reagents due to its reactive aldehyde and boronate functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) for client-directed synthesis projects.

Basic Information

Product Name	Benzaldehyde, 4-(Phenylmethoxy)-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	2130752-37-1
Molecular Formula	C20H23BO4
Molecular Weight	338.21 g/mol
Synonyms	4-(Benzyloxy)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 2-Formyl-5-(phenylmethoxy)phenylboronic acid pinacol ester; (4-(Benzyloxy)-2-formylphenyl)boronic acid pinacol ester; 4-Benzyloxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; PINACOL [4-(BENZYLOXY)-2-FORMYLPHENYL]BORONATE; B-[4-(Benzyloxy)-2-formylphenyl]boronic acid pinacol ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Benzaldehyde, 4-(Phenylmethoxy)-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 97%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.