Description

Potassium [(2-Chlorophenyl)Methyl]Trifluoroboranuide is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its value lies in its exceptional stability and reactivity as a nucleophilic coupling partner, enabling efficient and selective carbon-carbon bond formation. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and other complex molecular architectures central to drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the research and scale-up production of active pharmaceutical ingredients (APIs), particularly those containing chlorinated aromatic systems.
• Agrochemical Development: Serves as a critical precursor in the synthesis of novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the creation of advanced organic electronic materials and liquid crystals.
• Process Chemistry & Scale-Up: Valued for its improved handling and stability compared to boronic acids in large-scale manufacturing processes.
• Library Synthesis for Drug Screening: Enables the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry.

Basic Information

Product Name	Potassium [(2-Chlorophenyl)Methyl]Trifluoroboranuide
CAS No.	2126821-80-3
Molecular Formula	C7H6BClF3K
Molecular Weight	232.48 g/mol
Synonyms	Potassium (2-Chlorobenzyl)trifluoroborate; Potassium [(2-Chlorophenyl)methyl]trifluoroboranuide; (2-Chlorobenzyl)trifluoroboronic acid potassium salt; Potassium 2-Chlorobenzyltrifluoroborate; 2-Chlorobenzyltrifluoroboronate Potassium; Potassium Trifluoro(2-chlorobenzyl)borate; K-2-Chlorobenzyltrifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium [(2-Chlorophenyl)Methyl]Trifluoroboranuide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (1H, 11B, 13C, 19F) and HPLC analysis, to ensure high chemical purity and consistent performance as a coupling reagent. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
1H NMR	Conforms to structure
11B NMR	Conforms to structure
19F NMR	Conforms to structure
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.