Description

(1-Cyclopropyl-1H-Pyrazol-5-Yl)Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a critical step in constructing complex molecular architectures. This compound is essential for researchers and manufacturers in pharmaceutical R&D, agrochemical discovery, and materials science who require reliable, high-quality boronic ester reagents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the research and development of novel crop protection agents and herbicides, leveraging its pyrazole core structure.
• Material Science Research: Serves as a precursor for creating functional organic materials, including organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and bioconjugates for studying biological processes and target engagement.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form new carbon-carbon bonds with high efficiency and selectivity.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry.

Basic Information

Product Name	(1-Cyclopropyl-1H-Pyrazol-5-Yl)Boronic Acid Pinacol Ester
CAS No.	2123477-78-9
Molecular Formula	C₁₂H₁₉BN₂O₂
Molecular Weight	234.11 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-cyclopropyl-1H-pyrazole; 1-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; (1-Cyclopropyl-1H-pyrazol-5-yl)boronic acid pinacol ester; 1-Cyclopropyl-1H-pyrazole-5-boronic acid pinacol ester; 1-Cyclopropyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; B-(1-Cyclopropyl-1H-pyrazol-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our (1-Cyclopropyl-1H-Pyrazol-5-Yl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound is moisture-sensitive (hygroscopic); therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.