Description

3-Bromo-2,5-Dichlorophenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block, specifically engineered for advanced cross-coupling reactions. This compound matters because it provides a protected boronic acid functionality, offering superior stability and handling characteristics compared to its free acid counterpart, which is critical for multi-step synthetic sequences. Pharmaceutical, agrochemical, and advanced materials researchers need this ester for the precise construction of complex, multi-substituted aromatic and heteroaromatic scaffolds in drug discovery and specialty chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds to create biaryl structures, a common motif in active pharmaceutical ingredients (APIs) and organic electronic materials.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly for constructing complex, halogen-differentiated aromatic cores.
• Agrochemical Active Ingredient Development: Serves as a building block for synthesizing new generations of herbicides, fungicides, and insecticides with specific activity profiles.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis or as a precursor for boron-containing functional materials.
• Material Science Research: Utilized in the creation of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) where precise aromatic architecture is required.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.

Basic Information

Product Name	3-Bromo-2,5-Dichlorophenylboronic Acid Pinacol Ester
CAS No.	2121515-15-7
Molecular Formula	C12H14BBrCl2O2
Molecular Weight	352.86 g/mol
Synonyms	2-(3-Bromo-2,5-dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3-Bromo-2,5-dichlorophenyl)boronic acid pinacol ester; 3-Bromo-2,5-dichlorobenzeneboronic acid pinacol ester; Pinacol (3-bromo-2,5-dichlorophenyl)boronate; B-(3-Bromo-2,5-dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 2121515-15-7
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,5-Dichlorophenylboronic Acid Pinacol Ester is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We are committed to supplying material that meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged manipulations to prevent hydrolysis of the boronic ester moiety.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.