Description

4-Chloro-5-Methyl-1,3-Dihydro-2,1-Benzoxaborol-1-Ol is a specialized benzoxaborole derivative, a class of compounds recognized for their unique reactivity and utility in advanced chemical synthesis. This compound serves as a critical high-purity building block for the development of novel pharmaceuticals, agrochemicals, and functional materials. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in boron chemistry, medicinal chemistry, and catalyst design.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in developing boron-based protease inhibitors and antimicrobial agents.
• Agrochemical Research: Used in creating advanced active ingredients for crop protection products, leveraging its bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and boron-containing advanced materials.
• Organic Synthesis Building Block: Utilized in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to introduce complex boronate ester functionalities.
• Chemical Biology Probe Development: Employed in designing molecular probes for studying enzyme mechanisms and biological pathways.
• Catalyst Ligand Synthesis: Acts as a precursor for novel ligand systems in homogeneous catalysis.

Basic Information

Product Name	4-Chloro-5-Methyl-1,3-Dihydro-2,1-Benzoxaborol-1-Ol
CAS No.	2121515-09-9
Molecular Formula	C8H8BClO2
Molecular Weight	182.41 g/mol
Synonyms	4-Chloro-5-methyl-2,1-benzoxaborol-1(3H)-ol; 5-Chloro-6-methyl-1,3-dihydro-2,1-benzoxaborol-1-ol; 4-Chloro-5-methyl-1-hydroxy-1,3-dihydro-2,1-benzoxaborole; 4-Chloro-5-methylbenzoxaborol-1-ol; CAS 2121515-09-9; 4-Chloro-5-methyl-1,3-dihydrobenzo[c][1,2]oxaborol-1-ol
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-5-Methyl-1,3-Dihydro-2,1-Benzoxaborol-1-Ol adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, NMR, and MS for comprehensive characterization and purity verification. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.