Description

4-Isopropoxy-3-Methylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and this boronic ester, crucial for synthesizing biaryl structures found in many pharmaceuticals.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing substituted biphenyl or aromatic ether motifs.
• Agrochemical Product Development: Employed in creating novel herbicides, fungicides, and insecticides where specific aromatic substitution patterns are required for activity.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Utilized in the synthesis of organic electronic materials, such as those for OLEDs or conductive polymers, where precise molecular structure controls properties.
• Chemical Biology & Probe Development: Serves as a building block for creating molecular probes and tags used in biochemical assays and diagnostic research.

Basic Information

Product Name	4-Isopropoxy-3-Methylphenylboronic Acid Pinacol Ester
CAS No.	2121514-93-8
Molecular Formula	C₁₇H₂₇BO₃
Molecular Weight	290.21 g/mol
Synonyms	2-(4-Isopropoxy-3-methylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4-Isopropoxy-3-methylbenzeneboronic acid pinacol ester; 3-Methyl-4-isopropoxybenzeneboronic acid pinacol ester; (4-Isopropoxy-3-methylphenyl)boronic acid pinacol ester; Boronic acid, B-(4-isopropoxy-3-methylphenyl)-, 1,1-dimethylethyl ester; 4-Isopropoxy-m-tolylboronic acid pinacol ester; PINACOL 4-ISOPROPOXY-3-METHYLPHENYLBORONATE
EINECS	Contact for details

Quality Control

Our 4-Isopropoxy-3-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The container should be kept tightly sealed in a dry inert atmosphere to maintain stability, as boronic esters can be sensitive to prolonged exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.