Description

2,5-Dimethyl-4-Hydroxymethylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound matters as a critical building block in cross-coupling reactions, enabling the efficient and precise construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed formation of carbon-carbon bonds, fundamental in constructing biaryl and heterobiaryl structures prevalent in drug candidates.
• Pharmaceutical Intermediate Synthesis: Serves as a versatile building block for the development of active pharmaceutical ingredients (APIs), especially those containing complex aromatic or heteroaromatic systems.
• Agrochemical Research & Development: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the boronic ester functionality allows for precise structural modification.
• Material Science & OLED Development: Employed in the creation of organic light-emitting diode (OLED) materials and other advanced organic electronic components requiring specific aromatic linkages.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in asymmetric catalysis and other transition metal-catalyzed processes.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and bioconjugates for studying biological processes and target engagement.

Basic Information

Product Name	2,5-Dimethyl-4-Hydroxymethylphenylboronic Acid Pinacol Ester
CAS No.	2121514-86-9
Molecular Formula	C15H23BO3
Molecular Weight	262.15 g/mol
Synonyms	(4-(Hydroxymethyl)-2,5-dimethylphenyl)boronic acid pinacol ester; 2,5-Dimethyl-4-(hydroxymethyl)benzeneboronic acid pinacol ester; 4-(Hydroxymethyl)-2,5-dimethylbenzeneboronic acid pinacol ester; Pinacol (4-(hydroxymethyl)-2,5-dimethylphenyl)boronate; 2,5-Dimethyl-4-(hydroxymethyl)phenylboronic acid pinacol ester; Boronic acid, B-[4-(hydroxymethyl)-2,5-dimethylphenyl]-, 1,1,1,1-tetramethyl-2-propanyl ester
EINECS	Contact for details

Quality Control

Our 2,5-Dimethyl-4-Hydroxymethylphenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We adhere to cGMP principles where applicable, and all products are supported by comprehensive analytical data. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.