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5-Bromo-2-Ethoxypyridine-3-Boronic Acid Pinacol Ester CAS NO 2121514-85-8


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CAS No.:2121514-85-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Bromo-2-Ethoxypyridine-3-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters because it serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds to construct complex biaryl and heterobiaryl structures in drug discovery.
  • Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
  • Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with improved efficacy.
  • Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its pyridine core.
  • Ligand and Catalyst Development: Useful for synthesizing novel ligands for metal catalysis and organocatalysts.
  • Chemical Biology Probes: Facilitates the creation of labeled compounds and molecular probes for biological mechanism studies.

Basic Information

Product Name 5-Bromo-2-Ethoxypyridine-3-Boronic Acid Pinacol Ester
CAS No. 2121514-85-8
Molecular Formula C13H19BBrNO3
Molecular Weight 328.01 g/mol
Synonyms 5-Bromo-2-ethoxy-3-pyridineboronic acid pinacol ester; 2-Ethoxy-5-bromopyridine-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-bromo-2-ethoxypyridine; 5-Bromo-2-ethoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; (5-Bromo-2-ethoxypyridin-3-yl)boronic acid pinacol ester
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized by advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and GC-MS are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥97.0% (Area %)
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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