Description

2,3,4-Trichloropyridine-5-Boronic Acid Pinacol Ester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex pyridine-based heterocycles found in active pharmaceutical ingredients (APIs), including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trichloropyridine moiety imparts specific biological activity.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials through cross-coupling reactions.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Facilitates discovery chemistry and method development in research laboratories exploring new synthetic pathways.

Basic Information

Product Name	2,3,4-Trichloropyridine-5-Boronic Acid Pinacol Ester
CAS No.	2121514-82-5
Molecular Formula	C11H11BCl3NO2
Molecular Weight	314.38 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3,4-trichloropyridine; (2,3,4-Trichloropyridin-5-yl)boronic acid pinacol ester; 2,3,4-Trichloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2,3,4-Trichloro-5-pyridineboronic acid pinacol ester; 5-Boronic acid pinacol ester-2,3,4-trichloropyridine; 2,3,4-Trichloro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; CAS 2121514-82-5
EINECS	Contact for details

Quality Control

Our 2,3,4-Trichloropyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and easily oxidized nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.