Description

4,4,5,5-Tetramethyl-2-(3,5-Dimethyl-4-Propan-2-Yloxy-Phenyl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester derivative designed for sophisticated organic synthesis. This compound is a critical building block in modern pharmaceutical and agrochemical research, enabling efficient cross-coupling reactions to construct complex molecular architectures. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking reliable, high-quality synthetic intermediates.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex biaryl structures, a common motif in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Development: Employed in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Advanced Material Research: Utilized in the development of organic semiconductors, OLED materials, and liquid crystals.
• Chemical Biology & Probe Development: Acts as a versatile handle for bioconjugation and the creation of molecular probes for diagnostic applications.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(3,5-Dimethyl-4-Propan-2-Yloxy-Phenyl)-1,3,2-Dioxaborolane
CAS No.	2121514-76-7
Molecular Formula	C19H29BO3
Molecular Weight	316.25 g/mol
Synonyms	2-(4-Isopropoxy-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Isopropoxy-3,5-dimethylbenzeneboronic acid pinacol ester; (4-Isopropoxy-3,5-dimethylphenyl)boronic acid pinacol ester; 3,5-Dimethyl-4-isopropoxyphenylboronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-[4-(propan-2-yloxy)-3,5-dimethylphenyl]-1,3,2-dioxaborolane; PINACOL (4-ISOPROPOXY-3,5-DIMETHYLPHENYL)BORONATE
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(3,5-Dimethyl-4-Propan-2-Yloxy-Phenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.