Description

3-Isopropoxy-4-Methylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl or vinyl groups, fundamental in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for complex, multi-substituted biaryl structures.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Used in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Facilitates the synthesis of tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	3-Isopropoxy-4-Methylphenylboronic Acid Pinacol Ester
CAS No.	2121514-73-4
Molecular Formula	C₁₆H₂₅BO₃
Molecular Weight	276.18 g/mol
Synonyms	3-Isopropoxy-4-methylbenzeneboronic acid pinacol ester; 4-Methyl-3-isopropoxybenzeneboronic acid pinacol ester; (3-Isopropoxy-4-methylphenyl)boronic acid pinacol ester; B-(3-Isopropoxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-(3-isopropoxy-4-methylphenyl)-1,3,2-dioxaborolane; 3-Isopropoxy-4-methylphenylboronic acid, pinacol ester; PINACOL 3-ISOPROPOXY-4-METHYLPHENYLBORONATE
EINECS	Contact for details

Quality Control

Our 3-Isopropoxy-4-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.