Description

3-Cyclobutylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific phenyl-cyclobutyl structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where precise molecular engineering is crucial.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and inhibitors.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel organoboron-based catalysts and ligands for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	3-Cyclobutylphenylboronic Acid Pinacol Ester
CAS No.	2121514-70-1
Molecular Formula	C₁₆H₂₃BO₂
Molecular Weight	258.17 g/mol
Synonyms	3-Cyclobutylbenzeneboronic Acid Pinacol Ester; 3-Cyclobutylphenylboronic Acid, Pinacol Ester; (3-Cyclobutylphenyl)boronic Acid Pinacol Ester; 2-(3-Cyclobutylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol 3-Cyclobutylphenylboronate; B-(3-Cyclobutylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 3-Cyclobutylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.