Description

(4-Fluorobenzofuran-2-Yl)Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily needed by pharmaceutical, agrochemical, and advanced materials researchers for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those containing benzofuran and fluorinated aromatic scaffolds.
• Agrochemical Synthesis: Used to create novel active ingredients for crop protection products, leveraging the stability of the pinacol ester.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is required.
• Cross-Coupling Reactions: Serves as a versatile boronic ester partner in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds.
• Chemical Library Development: Used in parallel and combinatorial synthesis for high-throughput screening in drug discovery programs.
• Ligand and Catalyst Preparation: Acts as a building block for synthesizing specialized ligands and organometallic catalysts.

Basic Information

Product Name	(4-Fluorobenzofuran-2-Yl)Boronic Acid Pinacol Ester
CAS No.	2121514-66-5
Molecular Formula	C₁₄H₁₆BFO₃
Molecular Weight	262.09 g/mol
Synonyms	4-Fluoro-2-benzofuranboronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-fluorobenzofuran; 4-Fluorobenzofuran-2-boronic acid pinacol ester; (4-Fluoro-1-benzofuran-2-yl)boronic acid pinacol ester; 4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzofuran; PINACOL (4-FLUOROBENZOFURAN-2-YL)BORONATE
EINECS	Contact for details

Quality Control

Our (4-Fluorobenzofuran-2-Yl)Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is analyzed using advanced techniques including NMR and HPLC. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.