Description

3-Methyl-4-(Methylthio)Phenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound matters because it serves as a key, stable building block for constructing complex molecules via cross-coupling reactions, offering superior shelf-life and handling characteristics compared to its free acid form. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of biaryl and heterobiaryl scaffolds prevalent in drug discovery.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing substituted phenyl or thioether motifs.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is required.
• Ligand and Catalyst Development: Useful precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology Probes: Can be utilized to create tagged molecules for studying biological processes and target engagement.

Basic Information

Product Name	3-Methyl-4-(Methylthio)Phenylboronic Acid, Pinacol Ester
CAS No.	2121514-43-8
Molecular Formula	C14H21BO2S
Molecular Weight	264.19 g/mol
Synonyms	4-Methyl-3-(Methylthio)Benzeneboronic Acid Pinacol Ester; (3-Methyl-4-(Methylthio)Phenyl)boronic Acid Pinacol Ester; 2-(3-Methyl-4-(Methylthio)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-dioxaborolane; Pinacol [3-Methyl-4-(Methylthio)Phenyl]boronate; 3-Methyl-4-(Methylthio)Benzeneboronic Acid Pinacol Ester; Boronic acid, B-[3-methyl-4-(methylthio)phenyl]-, 1,1-dimethylethyl ester (9CI); CAS 2121514-43-8
EINECS	Contact for details

Quality Control

Our 3-Methyl-4-(Methylthio)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Each lot is analyzed via advanced chromatographic and spectroscopic methods. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.