Description

2,3-Difluoro-6-Chlorophenylboronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block in modern synthetic chemistry. Its value lies in its role as a protected boronic acid derivative, offering enhanced stability and handling characteristics for complex cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl scaffolds prevalent in drug discovery.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex, multi-substituted aromatic systems.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is critical.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Facilitates the creation of labeled compounds and molecular probes for biochemical and diagnostic applications.

Basic Information

Product Name	2,3-Difluoro-6-Chlorophenylboronic Acid Pinacol Ester
CAS No.	2121514-33-6
Molecular Formula	C12H14BClF2O2
Molecular Weight	274.50 g/mol
Synonyms	2,3-Difluoro-6-chlorophenylboronic acid pinacol ester; 2-Chloro-3,4-difluorophenylboronic acid pinacol ester; (2,3-Difluoro-6-chlorophenyl)boronic acid pinacol ester; 4-Chloro-2,3-difluorophenylboronic acid pinacol ester; Pinacol (2,3-difluoro-6-chlorophenyl)boronate; 2,3-Difluoro-6-chlorobenzeneboronic acid pinacol ester; B-(2,3-Difluoro-6-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. Each batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results from HPLC, NMR, and other analytical methods are available upon request. We adhere to a quality management system to guarantee supply reliability and product integrity for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.