Description

4-Chloro-2,3-Dimethylphenylboronic Acid Pinacol Ester CAS NO 2121514-19-8 is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides by constructing complex aryl-aryl bonds.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs and semiconductors, due to its stable boronate ester functionality.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes and inhibitors.
• Academic & Industrial R&D: A fundamental tool for methodology development and exploring new reaction pathways in organic synthesis laboratories worldwide.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts.

Basic Information

Product Name	4-Chloro-2,3-Dimethylphenylboronic Acid Pinacol Ester
CAS No.	2121514-19-8
Molecular Formula	C14H20BClO2
Molecular Weight	266.57 g/mol
Synonyms	4-Chloro-2,3-dimethylbenzeneboronic acid pinacol ester; (4-Chloro-2,3-dimethylphenyl)boronic acid pinacol ester; 2-(4-Chloro-2,3-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Chloro-2,3-dimethylphenylboronic acid, pinacol ester; Boronic acid, B-(4-chloro-2,3-dimethylphenyl)-, 1,1-dimethylethyl ester; CAS 2121514-19-8
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,3-Dimethylphenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.