Description

3,4-Dichloro-2-Formylphenylboronic Acid Pinacol Ester is a high-value, multifunctional boronic ester building block designed for advanced organic synthesis. This compound is critical for facilitating efficient cross-coupling reactions, enabling the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

This versatile boronic ester serves as a key intermediate in several high-value synthetic pathways:

• Suzuki-Miyaura Cross-Coupling Reactions: As a stable, air-tolerant boronate reagent for constructing biaryl and heterobiaryl systems central to drug discovery.
• Pharmaceutical Intermediate Synthesis: For the research and development of new active pharmaceutical ingredients (APIs), leveraging its reactive formyl and boronate functional groups.
• Agrochemical Research: In the creation of novel herbicides, fungicides, and insecticides requiring complex, halogenated aromatic scaffolds.
• Material Science & OLED Development: As a building block for synthesizing organic electronic materials, ligands, and functional polymers.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and inhibitors for biochemical research.

Basic Information

Product Name	3,4-Dichloro-2-Formylphenylboronic Acid Pinacol Ester
CAS No.	2121514-14-3
Molecular Formula	C13H15BCl2O3
Molecular Weight	301.38 g/mol
Synonyms	2-Formyl-3,4-dichlorophenylboronic acid pinacol ester; (3,4-Dichloro-2-formylphenyl)boronic acid pinacol ester; 3,4-Dichloro-2-formylbenzeneboronic acid pinacol ester; Pinacol (3,4-dichloro-2-formylphenyl)boronate; CAS 2121514-14-3; 3,4-Dichloro-2-carboxaldehydephenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 3,4-Dichloro-2-Formylphenylboronic Acid Pinacol Ester is manufactured and tested under strict quality management protocols. Our products undergo rigorous analytical testing, including NMR, HPLC, and LC-MS, to ensure identity, purity, and consistency meet the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.