Description

5-Bromo-4-Chloropyridine-3-Boronic Acid Pinacol Ester is a high-value, multi-functional boronic ester building block crucial for modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, to construct complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex pyridine derivatives.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific halogenated pyridine structures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling Reactions: The pinacol boronic ester group makes it an ideal partner for palladium-catalyzed coupling with various aryl/heteroaryl halides, enabling rapid diversification of molecular libraries.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	5-Bromo-4-Chloropyridine-3-Boronic Acid Pinacol Ester
CAS No.	2121514-13-2
Molecular Formula	C11H14BBrClNO2
Molecular Weight	318.40 g/mol
Synonyms	(5-Bromo-4-chloropyridin-3-yl)boronic acid pinacol ester; 4-Chloro-5-bromopyridine-3-boronic acid pinacol ester; 3-Bromo-4-chloropyridine-5-boronic acid pinacol ester; 5-Bromo-4-chloro-3-pyridineboronic acid pinacol ester; Pinacol (5-bromo-4-chloropyridin-3-yl)boronate; B-(5-Bromo-4-chloro-3-pyridinyl)boronic acid pinacol ester; 2121514-13-2; 5-Br-4-Cl-Py-3-Bpin
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloropyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality ensures material consistency and reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.