Description

2,3,4-Trimethoxyphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for forming carbon-carbon bonds. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex, multi-substituted aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl coupling steps.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics, via cross-coupling polymerization or functionalization.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands or organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Synthesis: Utilized to create molecular probes and bioconjugates for studying biological systems and developing diagnostic tools.
• Academic & Industrial R&D: A versatile reagent for methodological development and exploratory synthesis in both university laboratories and industrial R&D centers.

Basic Information

Product Name	2,3,4-Trimethoxyphenylboronic Acid, Pinacol Ester
CAS No.	2121514-09-6
Molecular Formula	C15H23BO5
Molecular Weight	294.15 g/mol
Synonyms	2,3,4-Trimethoxyphenylboronic Acid Pinacol Ester; (2,3,4-Trimethoxyphenyl)boronic Acid Pinacol Ester; 2,3,4-Trimethoxyphenyl-1,3,2-dioxaborinane, 2-(2,3,4-Trimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-(2,3,4-trimethoxyphenyl)-1,3,2-dioxaborolane; Pinacol 2,3,4-Trimethoxyphenylboronate; Boronic acid, B-(2,3,4-trimethoxyphenyl)-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our 2,3,4-Trimethoxyphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring traceability and consistency, from early-stage research to scale-up development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture and prevent degradation. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.