Description

3,5-Dimethyl-4-Hydroxymethylphenylboronic Acid Pinacol Ester is a high-value, protected boronic acid derivative essential for modern synthetic chemistry. Its primary value lies in its enhanced stability and solubility compared to the free boronic acid, making it a superior reagent for critical cross-coupling reactions. This compound is a key building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular construction is paramount.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of complex biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Used in the research and production of active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides requiring specific aromatic frameworks.
• Ligand and Catalyst Development: Employed in the creation of novel organometallic complexes and chiral ligands for asymmetric catalysis.
• Organic Electronic Materials: A precursor in the synthesis of conjugated polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors due to its selective reactivity.

Basic Information

Product Name	3,5-Dimethyl-4-Hydroxymethylphenylboronic Acid Pinacol Ester
CAS No.	2121514-08-5
Molecular Formula	C15H23BO3
Molecular Weight	262.15 g/mol
Synonyms	4-(Hydroxymethyl)-3,5-dimethylbenzeneboronic Acid Pinacol Ester; (4-(Hydroxymethyl)-3,5-dimethylphenyl)boronic Acid Pinacol Ester; 3,5-Dimethyl-4-(hydroxymethyl)phenylboronic Acid Pinacol Ester; Pinacol (4-(Hydroxymethyl)-3,5-dimethylphenyl)boronate; 2-(4-(Hydroxymethyl)-3,5-dimethylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; B-(4-(Hydroxymethyl)-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 3,5-Dimethyl-4-Hydroxymethylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive applications. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.