Description

4,5-Dimethyl-2-Ethoxyphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex biaryl and heterobiaryl structures for active ingredient development.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those containing complex aryl-aryl linkages.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific biaryl motifs.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as polymers for OLEDs or organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organometallic complexes.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A reliable starting material for custom synthesis projects requiring precise, air- and moisture-stable boronic ester couplings.

Basic Information

Item	Details
Product Name	4,5-Dimethyl-2-Ethoxyphenylboronic Acid, Pinacol Ester
CAS No.	2121514-05-2
Molecular Formula	C16H25BO3
Molecular Weight	276.18 g/mol
Synonyms	2-Ethoxy-4,5-dimethylphenylboronic acid pinacol ester; 4,5-Dimethyl-2-ethoxyphenylboronic acid pinanediol ester (common misnomer); (4,5-Dimethyl-2-ethoxyphenyl)boronic acid pinacol ester; Pinacol (4,5-dimethyl-2-ethoxyphenyl)boronate; 2-(4,5-Dimethyl-2-ethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-(4,5-dimethyl-2-ethoxyphenyl)-, 1,1-dimethylethyl ester (related); CAS 2121514-05-2.
EINECS	Contact for details

Quality Control

Our 4,5-Dimethyl-2-Ethoxyphenylboronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including NMR (¹H, ¹³C, ¹¹B) and HPLC to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent hydrolysis and maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.