Description

3-Bromo-2-(Methylthio)Phenylboronic Acid is a specialized organoboronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its unique substitution pattern, which allows for selective cross-coupling reactions to construct complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the bromo and methylthio groups offer specific reactivity and functionality.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the global life sciences market.

Basic Information

Item	Detail
Product Name	3-Bromo-2-(Methylthio)Phenylboronic Acid
CAS No.	2121513-98-0
Molecular Formula	C7H8BBrO2S
Molecular Weight	247.92 g/mol
Synonyms	[2-Bromo-6-(Methylthio)Phenyl]Boronic Acid; (3-Bromo-2-(Methylsulfanyl)Phenyl)Boronic Acid; 3-Bromo-2-(Methylmercapto)Benzeneboronic Acid; 2-Bromo-6-(Methylthio)Benzeneboronic Acid; Boronic acid, B-[3-bromo-2-(methylthio)phenyl]-; 2121513-98-0; (3-Bromo-2-methylsulfanylphenyl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-(Methylthio)Phenylboronic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade typically meets a purity specification of ≥95% (by HPLC), with detailed impurity profiling available. Certificates of Analysis (COA) are provided with each shipment, documenting identity, assay, and purity. We support compliance with cGMP and ICH guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.