Description

5-Chloro-2-Fluoro-3-(Trifluoromethyl)Phenylboronic Acid is a high-purity, multi-functional boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that benefit from the stability imparted by the trifluoromethyl and halogen groups.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, liquid crystals, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to introduce the substituted phenyl ring into complex molecules.
• Chemical Biology & Diagnostics: Employed in the development of molecular probes, sensors, and bioconjugation agents due to its boronic acid functionality.

Basic Information

Product Name	5-Chloro-2-Fluoro-3-(Trifluoromethyl)Phenylboronic Acid
CAS No.	2121513-80-0
Molecular Formula	C7H4BClF4O2
Molecular Weight	241.37 g/mol
Synonyms	[5-Chloro-2-fluoro-3-(trifluoromethyl)phenyl]boronic acid; 5-Chloro-2-fluoro-3-(trifluoromethyl)benzeneboronic acid; (5-Chloro-2-fluoro-3-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[5-chloro-2-fluoro-3-(trifluoromethyl)phenyl]-; 3-Trifluoromethyl-5-chloro-2-fluorophenylboronic acid; 2121513-80-0
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-3-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.