Description

4-Carboxy-3-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is a high-value, multifunctional boronic ester building block. This compound is critical for enabling efficient cross-coupling reactions, particularly in the synthesis of complex molecules where the carboxylic acid and trifluoromethyl groups are required. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that incorporate the trifluoromethyl group for enhanced bioactivity and stability.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: The boronic ester and carboxylic acid functionalities make it useful for synthesizing novel ligands for catalysis.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and sensors for biological imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, complex aromatic structures.

Basic Information

Product Name	4-Carboxy-3-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester
CAS No.	2121513-72-0
Molecular Formula	C15H18BF3O4
Molecular Weight	330.11 g/mol
Synonyms	[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzoic Acid]; 2-(Trifluoromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid; 4-Carboxy-3-trifluoromethylbenzeneboronic Acid Pinacol Ester; 4-Borono-2-(trifluoromethyl)benzoic Acid Pinacol Ester; Pinacol [4-Carboxy-3-(trifluoromethyl)phenyl]boronate
EINECS	Contact for details

Quality Control

Our 4-Carboxy-3-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.