Description

2,6-Dimethoxy-5-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, advanced pharmaceutical intermediate and building block featuring a pinacol boronate ester group. This compound is essential for modern synthetic chemistry, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily sought after by R&D and process chemistry teams in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for novel drug candidates targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its boronate group for creating diverse aromatic structures.
• Material Science Research: Serves as a precursor for organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds between aromatic and heteroaromatic systems.
• Chemical Biology & Medicinal Chemistry: Utilized in the design and synthesis of molecular probes, enzyme inhibitors, and compound libraries for high-throughput screening.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and commercial production under cGMP guidelines.

Basic Information

Item	Details
Product Name	2,6-Dimethoxy-5-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	2121513-65-1
Molecular Formula	C15H24BNO4
Molecular Weight	293.17 g/mol
Synonyms	5-Methyl-2,6-dimethoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Pyridineboronic acid, 2,6-dimethoxy-5-methyl-, pinacol ester; 2,6-Dimethoxy-5-methylpyridine-3-boronic acid pinacol ester; (2,6-Dimethoxy-5-methylpyridin-3-yl)boronic acid pinacol ester; CAS 2121513-65-1; Boronate ester of 2,6-dimethoxy-5-methylpyridine-3-boronic acid
EINECS	Contact for details

Quality Control

Every batch of our 2,6-Dimethoxy-5-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive cross-coupling and pharmaceutical applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and other spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.