Description

3,6-Difluoro-2-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific fluorinated aromatic motifs.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where its structure aids in tuning electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of fluorinated probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	3,6-Difluoro-2-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	2121513-59-3
Molecular Formula	C14H19BF2O3
Molecular Weight	284.11 g/mol
Synonyms	2-(3,6-Difluoro-2-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; (3,6-Difluoro-2-methoxyphenyl)boronic acid pinacol ester; 3,6-Difluoro-2-methoxybenzeneboronic acid pinacol ester; 2-Methoxy-3,6-difluorophenylboronic acid pinacol ester; Pinacol (3,6-difluoro-2-methoxyphenyl)boronate; CAS 2121513-59-3
EINECS	Contact for details

Quality Control

Our 3,6-Difluoro-2-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.