Description

5-Fluoro-2-(Ethoxy)-Pyridine-4-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the precise and efficient construction of complex fluorinated heterocyclic scaffolds, which are critical motifs in advanced material and pharmaceutical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated pyridine derivatives with potential biological activity.
• Agrochemical Research: Used to construct novel heterocyclic compounds for the development of new herbicides, fungicides, and insecticides.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or charge-transport molecules.
• Chemical Synthesis: Enables the introduction of the 5-fluoro-2-ethoxypyridine moiety into more complex molecular architectures under mild conditions.
• Library Synthesis: Ideal for medicinal chemistry programs focused on generating diverse compound libraries for high-throughput screening.
• Ligand & Catalyst Development: Can be utilized to synthesize novel bidentate or tridentate ligands for catalytic systems.

Basic Information

Product Name	5-Fluoro-2-(Ethoxy)-Pyridine-4-Boronic Acid Pinacol Ester
CAS No.	2121513-50-4
Molecular Formula	C13H19BFNO3
Molecular Weight	267.11 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-[5-fluoro-2-(ethoxy)pyridin-4-yl]-1,3,2-dioxaborolane; 5-Fluoro-2-ethoxypyridine-4-boronic acid pinacol ester; 2-(5-Fluoro-2-ethoxypyridin-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-fluoro-2-ethoxypyridine; 5-Fluoro-2-ethoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Ethoxy)-Pyridine-4-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.