Description

2-(3,4-Dichloro-2-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and development. The CAS number for this compound is 2121513-28-6.

Application

This versatile boronic ester is primarily utilized as a key synthetic intermediate. Its applications include:

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex, substituted aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific chlorinated aromatic motifs.
• Material Science Research: Acts as a monomer or precursor in the development of organic electronic materials, such as polymers for OLEDs or conductive films.
• Cross-Coupling Reactions: Specifically designed for use in palladium-catalyzed Suzuki-Miyaura cross-coupling to construct biaryl and heterobiaryl structures with high efficiency.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and labeled compounds for biochemical and diagnostic research.

Basic Information

Item	Detail
Product Name	2-(3,4-Dichloro-2-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2121513-28-6
Molecular Formula	C13H17BCl2O3
Molecular Weight	303.00 g/mol
Synonyms	2-(3,4-Dichloro-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3,4-Dichloro-2-methoxyphenyl)boronic acid pinacol ester; 3,4-Dichloro-2-methoxybenzeneboronic acid pinacol ester; (3,4-Dichloro-2-methoxyphenyl)BPin; Pinacol (3,4-dichloro-2-methoxyphenyl)boronate; 2-Methoxy-3,4-dichlorophenylboronic acid pinacol ester; CAS 2121513-28-6
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dichloro-2-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity (typically by HPLC/NMR), identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical: 98-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.