Description

3-Chloro-2-Methoxy-4-Methylphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical synthesis. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl or heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific substituted phenyl groups.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics, via polymerization or functionalization.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis or as a building block for metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for the synthesis of tagged molecules or probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise boronic ester.

Basic Information

Item	Details
Product Name	3-Chloro-2-Methoxy-4-Methylphenylboronic Acid Pinacol Ester
CAS No.	2121513-15-1
Molecular Formula	C14H20BClO3
Molecular Weight	282.57 g/mol
Synonyms	2-Chloro-6-Methoxy-3-Methylphenylboronic Acid Pinacol Ester; (3-Chloro-2-methoxy-4-methylphenyl)boronic Acid Pinacol Ester; 4-Chloro-3-Methoxy-2-Methylbenzeneboronic Acid Pinacol Ester; Pinacol (3-Chloro-2-methoxy-4-methylphenyl)boronate; CAS 2121513-15-1; Boronic acid, B-(3-chloro-2-methoxy-4-methylphenyl)-, 1,1-dimethylethyl ester; 3-Chloro-2-methoxy-4-methylbenzeneboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Methoxy-4-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full batch data are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (H-NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.