Description

1-Bromo-3-Chloro-2-Ethoxy-5-Fluorobenzene is a high-purity, multi-substituted benzene derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in the development of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and process chemists in fine chemical synthesis, where its unique halogen and ether substitution pattern enables precise molecular construction.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring a specific halogenated aromatic core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its fluorinated and halogenated structure.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex functionalities.
• Chemical Research & Development: A valuable reagent for medicinal chemistry programs and process optimization in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	1-Bromo-3-Chloro-2-Ethoxy-5-Fluorobenzene
CAS No.	2121513-07-1
Molecular Formula	C8H7BrClFO
Molecular Weight	253.50 g/mol
Synonyms	2-Bromo-6-Chloro-3-Ethoxyfluorobenzene; 3-Chloro-2-ethoxy-5-fluorobromobenzene; 5-Fluoro-2-ethoxy-1-bromo-3-chlorobenzene; Benzene, 1-bromo-3-chloro-2-ethoxy-5-fluoro-; 1-Bromo-3-chloro-2-ethoxy-5-fluoro-benzene; 2-Ethoxy-5-fluoro-1-bromo-3-chlorobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-2-Ethoxy-5-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.