Description

4,4,5,5-Tetramethyl-2-(5-Methyl-2-Propan-2-Yloxy-Phenyl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its stability and reactivity, making it an essential reagent for constructing complex molecular architectures through cross-coupling reactions. This compound is primarily needed by research and development laboratories, pharmaceutical intermediates manufacturers, and agrochemical producers for creating novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and this boronic ester, crucial for synthesizing biaryl structures in drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the development and scale-up of active pharmaceutical ingredients (APIs), particularly those containing complex, substituted aromatic systems.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require specific, sterically hindered biphenyl motifs.
• Material Science & OLED Development: Acts as a precursor for creating organic light-emitting diode (OLED) materials and other advanced organic electronic components.
• Ligand and Catalyst Preparation: Useful in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: Serves as a versatile tool for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(5-Methyl-2-Propan-2-Yloxy-Phenyl)-1,3,2-Dioxaborolane
CAS No.	2121512-73-8
Molecular Formula	C₁₇H₂₅BO₃
Molecular Weight	288.19 g/mol
Synonyms	2-(5-Methyl-2-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (5-Methyl-2-isopropoxyphenyl)boronic acid pinacol ester; 2-Isopropoxy-5-methylphenylboronic acid pinacol ester; 5-Methyl-2-isopropoxybenzeneboronic acid pinacol ester; Pinacol [5-methyl-2-(propan-2-yloxy)phenyl]boronate; CAS 2121512-73-8; Boronic ester derivative of 2-isopropoxy-5-methylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(5-Methyl-2-Propan-2-Yloxy-Phenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) and spectroscopic confirmation (NMR) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.