Description

2,4-Dichloro-5-Methylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this boronic ester, fundamental in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing a substituted biphenyl or heterobiaryl core.
• Agrochemical Synthesis: Serves as a precursor in creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and organometallic complexes.
• Material Science Research: A building block for organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology Probes: Useful for synthesizing tagged molecules for studying biological processes and target engagement.

Basic Information

Product Name	2,4-Dichloro-5-Methylphenylboronic Acid Pinacol Ester
CAS No.	2121512-39-6
Molecular Formula	C13H17BCl2O2
Molecular Weight	287.99 g/mol
Synonyms	2,4-Dichloro-5-methylbenzeneboronic acid pinacol ester; (2,4-Dichloro-5-methylphenyl)boronic acid pinacol ester; 5-Methyl-2,4-dichlorophenylboronic acid pinacol ester; B-(2,4-Dichloro-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2,4-Dichloro-5-methylphenyl-Bpin; 2,4-Dichloro-5-methylphenylBPin; Pinacol (2,4-dichloro-5-methylphenyl)boronate
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistent performance in sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.