Description

2-Bromo-5-Iodophenylboronic Acid Pinacol Ester is a high-purity, multi-halogenated boronic ester building block essential for modern synthetic chemistry. Its value lies in its dual functionality, offering orthogonal reactivity for sequential cross-coupling reactions, such as Suzuki-Miyaura couplings, which are fundamental to constructing complex molecular architectures. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing active pharmaceutical ingredients (APIs), advanced ligands, and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing biaryl and heterobiaryl scaffolds prevalent in drug discovery and API development.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific halogenated aromatic structures.
• Material Science Precursor: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds with high selectivity.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes, tags, and inhibitors for biological target identification.
• Academic & Contract Research: A valuable reagent for methodological development and custom synthesis projects in R&D laboratories.

Basic Information

Product Name	2-Bromo-5-Iodophenylboronic Acid Pinacol Ester
CAS No.	2121512-32-9
Molecular Formula	C12H15BBrIO2
Molecular Weight	407.87 g/mol
Synonyms	2-Bromo-5-iodobenzeneboronic acid pinacol ester; (2-Bromo-5-iodophenyl)boronic acid pinacol ester; 5-Bromo-2-iodophenylboronic acid pinacol ester; 2-Bromo-5-iodophenyl-Bpin; B-(2-Bromo-5-iodophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (2-bromo-5-iodophenyl)boronate; 2121512-32-9
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Iodophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.