Description

3,5-Dimethyl-2-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound matters for its stability and utility as a key intermediate in modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between aryl halides and this boronic ester derivative, essential for constructing biaryl structures in drug discovery.
• Pharmaceutical Intermediate: Serves as a protected boronic acid precursor in the synthesis of active pharmaceutical ingredients (APIs) and candidate molecules, particularly those containing a substituted methoxyphenyl moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where specific aromatic ring systems are required.
• Ligand and Catalyst Development: Employed as a starting material for creating specialized ligands or metal-organic frameworks (MOFs) with tailored properties.
• Material Science Research: Utilized in the synthesis of organic electronic materials, such as those for OLEDs or conductive polymers, where precise molecular structure controls function.
• Chemical Biology Probes: Acts as a building block for creating molecular probes and tags used in biochemical assays and diagnostic research.

Basic Information

Product Name	3,5-Dimethyl-2-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	2121512-20-5
Molecular Formula	C15H23BO3
Molecular Weight	262.15 g/mol
Synonyms	2-Methoxy-3,5-dimethylbenzeneboronic Acid Pinacol Ester; (2-Methoxy-3,5-dimethylphenyl)boronic Acid Pinacol Ester; 3,5-Dimethyl-2-methoxyphenylboronic Acid Pinanediol Ester (common alternative); Pinacol (3,5-Dimethyl-2-methoxyphenyl)boronate; B-(2-Methoxy-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-(2-methoxy-3,5-dimethylphenyl)-, 1,1-dimethylethyl ester (related); CAS 2121512-20-5
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and process chemistry. Every batch is characterized by NMR (1H, 13C, 11B), HPLC, and GC analysis to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.