Description

5-Bromo-2,6-Dimethoxypyridine-3-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters for its role as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl and heterobiaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex heterocyclic compounds and exploring new chemical spaces.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Library Synthesis: Ideal for parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	5-Bromo-2,6-Dimethoxypyridine-3-Boronic Acid Pinacol Ester
CAS No.	2121511-88-2
Molecular Formula	C13H19BBrNO4
Molecular Weight	344.01 g/mol
Synonyms	5-Bromo-2,6-dimethoxypyridine-3-boronic acid pinacol ester; 3-Bromo-2,6-dimethoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2,6-Dimethoxy-5-bromopyridine-3-boronic acid pinacol ester; (5-Bromo-2,6-dimethoxypyridin-3-yl)boronic acid pinacol ester; 5-Bromo-2,6-dimethoxy-3-pyridineboronic acid pinacol ester; Pinacol (5-bromo-2,6-dimethoxypyridin-3-yl)boronate
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,6-Dimethoxypyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.