Description

(3-Bromo-2,6-dimethoxypyridin-4-yl)boronic acid pinacol ester is a high-purity, functionalized pyridine boronic ester building block essential for modern synthetic chemistry. This compound matters because it enables precise Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need this reagent for the efficient synthesis of novel active ingredients and functional molecules, where the bromo and dimethoxy substituents offer unique regiochemical control and electronic properties.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex pyridine-based scaffolds.
• Material Science: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and charge-transport materials.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes, bioconjugation linkers, and tags for studying biological systems.
• Catalyst & Ligand Development: Used to construct novel nitrogen-containing ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(3-Bromo-2,6-dimethoxypyridin-4-yl)boronic acid pinacol ester
CAS No.	2121511-86-0
Molecular Formula	C₁₃H₁₉BBrNO₄
Molecular Weight	344.01 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-(3-bromo-2,6-dimethoxypyridin-4-yl)-1,3,2-dioxaborolane; 2-(3-Bromo-2,6-dimethoxypyridin-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3-Bromo-2,6-dimethoxy-4-pyridinyl)boronic acid pinacol ester; 3-Bromo-2,6-dimethoxypyridine-4-boronic acid pinacol ester; B-(3-Bromo-2,6-dimethoxy-4-pyridinyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our (3-Bromo-2,6-dimethoxypyridin-4-yl)boronic acid pinacol ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (argon/nitrogen) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.