Description

2-(4-Chloro-3-Isopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient and selective carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for complex molecule synthesis. The product is supplied with a CAS number of 2121511-69-9.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific aryl-chloro substitution patterns.
• Material Science: Serves as a precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic pathways and novel compound libraries.
• Ligand and Catalyst Development: Useful in the synthesis of specialized ligands for transition metal catalysis.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Item	Detail
Product Name	2-(4-Chloro-3-Isopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2121511-69-9
Molecular Formula	C15H22BClO2
Molecular Weight	280.60 g/mol
Synonyms	4-Chloro-3-isopropylbenzeneboronic acid pinacol ester; (4-Chloro-3-isopropylphenyl)boronic acid pinacol ester; 2-(4-Chloro-3-propan-2-ylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Chloro-3-isopropylphenylboronic acid pinacol ester; 4-Chloro-3-(1-methylethyl)benzeneboronic acid pinacol ester; PINACOL (4-CHLORO-3-ISOPROPYLPHENYL)BORONATE
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Chloro-3-Isopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency required for sensitive coupling reactions. Our quality assurance protocols are designed to support cGMP and ISO 9001 compliant manufacturing environments. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (NMR)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.