Description

4-Bromo-3-Methylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and boronic acids, fundamental in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of new drug candidates, particularly those containing complex biaryl structures.
• Agrochemical Product Development: Employed in creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science & OLED Research: Acts as a precursor for synthesizing organic semiconductors, ligands for catalysts, and luminescent materials.
• Chemical Biology & Probe Development: Useful for tagging and modifying biomolecules in research applications.
• Scale-up and Process Chemistry: The pinacol ester protection offers improved stability and handling for large-scale manufacturing processes.

Basic Information

Product Name	4-Bromo-3-Methylphenylboronic Acid Pinacol Ester
CAS No.	2121511-60-0
Molecular Formula	C₁₃H₁₈BBrO₂
Molecular Weight	297.00 g/mol
Synonyms	4-Bromo-3-methylbenzeneboronic acid pinacol ester; 2-(4-Bromo-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (4-Bromo-3-methylphenyl)boronic acid pinacol ester; 4-Bromo-m-tolylboronic acid pinacol ester; Pinacol (4-bromo-3-methylphenyl)boronate; CAS 2121511-60-0; BRN 9087755
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.