Description

5-Chloro-2-Ethoxypyridine-3-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is critical for facilitating efficient cross-coupling reactions, enabling the rapid construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between pyridine derivatives and aryl/heteroaryl halides.
• Pharmaceutical Intermediate: Used in the research and synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Serves as a building block for creating new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, ligands for catalysts, and electron-transport materials for electronic devices.
• Chemical Biology & Probe Development: Useful for creating tagged molecules and bioconjugates for studying biological pathways.
• Scale-up & Process Chemistry: Suitable for transitioning from milligram-scale discovery to kilogram-scale production under GMP-like conditions.

Basic Information

Product Name	5-Chloro-2-Ethoxypyridine-3-Boronic Acid Pinacol Ester
CAS No.	2121511-53-1
Molecular Formula	C13H19BClNO3
Molecular Weight	283.56 g/mol
Synonyms	5-Chloro-2-ethoxypyridine-3-boronic acid pinacol ester; (5-Chloro-2-ethoxypyridin-3-yl)boronic acid pinacol ester; 3-Borono-5-chloro-2-ethoxypyridine pinacol ester; 5-Chloro-2-ethoxy-3-pyridineboronic acid pinacol ester; Pinacol (5-chloro-2-ethoxypyridin-3-yl)boronate; B-(5-Chloro-2-ethoxypyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 2121511-53-1
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Ethoxypyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.